Almac Diagnostic Services’ Katarina Wikstrom

She obtained a PhD in experimental pathology from Lund University, and subsequently completed a postdoctoral fellowship on the molecular mechanisms of prostanoid signaling in vascular haemostasis and oncology at University College Dublin.

Could you give us an overview of your work?

Almac Diagnostic Services supports Pharma and Biotech in the discovery, development and commercialization of biomarkers to identify patients that will respond to their therapeutics. I have global responsibility for Product Development, which means that I oversee the cross-functional teams (Assay development and validation, Biostatistics, Software and Manufacturing) that develop, validate and manufacture the laboratory-based tests that are used to detect these biomarkers. The continued emergence of personalized medicine, with a large proportion of new medicines requiring a diagnostic test to identity patients that will benefit from treatment, has put Diagnostic companies such as Almac Diagnostic Services on the critical path towards drug approvals for the pharmaceutical industry. As a result, we work very closely, and in a highly collaborative manner, with our Pharma partners to ensure that development of the diagnostic is aligned with drug development, enabling contemporaneous regulatory approval and market launch.

When did you realize you were interested in science? As a young child, teen, or older?

I had a general interest in science as far back as I can remember, especially anything to do with human biology always seemed to fascinate me. My grandmother would fuel this interest by telling me stories of unusual illnesses and ailments, which is perhaps why I used to say I wanted to be a doctor when I grew up. However, I don’t think that my interest in science was properly ignited until at the age of 13 I was lucky enough to get an extremely inspiring chemistry teacher. He did what all good teachers do and brought us as students along on a journey of discovery, opening this entirely new world to me, and from then I was hooked. As I studied more chemistry, I found that the organic side fascinated me the most, which ultimately led me on to cellular and molecular biology – possibly because it tied in to that very early interest in human health and disease.

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